What is the catalog number for MYH8 Antibody?

The catalog number for MYH8 Antibody is 8081.

What sizes are available for MYH8 Antibody?

MYH8 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does MYH8 Antibody come in?

MYH8 Antibody is available in 2 different pack sizes.

Is MYH8 Antibody in stock?

MYH8 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MYH8 Antibody

Product Specifications

Background

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells (1) . MYH8 (myosin, heavy chain 8, skeletal muscle, perinatal) is a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction (2,3) . This gene is predominantly expressed in fetal skeletal muscle. MYH8 is regulated by phosphorylation via myosin light chain kinase (MLCK) and by intracellular Ca2+ concentrations (3) . A mutation in this gene results in trismus-pseudocamptodactyly syndrome (4) .

NCBI Gene ID

4626

Swiss Prot

P13535

Accession Number

NP_002463

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

MYH8 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1201 - HeLa Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Horse: (95%), Rabbit: (95%), Pig: (89%), Bovine: (89%), Chicken: (89%)

Buffer

MYH8 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

MYH8 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

MYH8 antibody is human, mouse and rat reactive. MYH8 antibody is predicted to not cross-react with other members of the myosin heavy chain family.

Symbol

MYH8

NCBI Official Name

Myosin, heavy chain 8, skeletal muscle, perinatal

NCBI Organism

Homo sapiens

Background Reference 01

Yu H, Waddell JN, Kuang S, et al. Park7 expression influences myotube size and myosin expression in muscle. PLoS One 2014; 9:e92030.

Background Reference 02

Feghali R and Leinwand LA. Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain. J. Cell Biol. 1989; 108:1791-7.

Background Reference 03

Jullian EH, Kelly AM, Pompidou AJ, et al. Characterization of a human perinatal myosin heavy-chain transcript. Eur. J. Biochem. 1995; 230:1001-6.

Background Reference 04

Minzer-Conzetti K, Wu E, Vargervik K, et al. Phenotypic variation in trismus-pseudocamptodactyly syndrome caused by a recurrent MYH8 mutation. Clin. Dysmorphol. 2008; 17:1-4.