What is the catalog number for CACNA1H Antibody?

The catalog number for CACNA1H Antibody is 8029.

What sizes are available for CACNA1H Antibody?

CACNA1H Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does CACNA1H Antibody come in?

CACNA1H Antibody is available in 2 different pack sizes.

Is CACNA1H Antibody in stock?

CACNA1H Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

CACNA1H Antibody

Product Specifications

Background

The calcium channel protein CACNA1H is a T-type member of the alpha-1 subunit family that is part of the voltage-dependent calcium channel complex which mediates the influx of calcium ions into the cell upon membrane polarization (1,2) . CACNA1H is a subunit of Cav3.2 T-type calcium channel that is involved in neurological disorders such as epilepsy and pain (2,3) . CACNA1H associates with the caveolin protein Cav-3 and it is thought that Cav-3 regulates the Protein Kinase A (PKA) modulation of CACNA1H-containing Cav3.2 T-type calcium channels (4) .

NCBI Gene ID

8912

Swiss Prot

O95180

Accession Number

NP_066921

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

CACNA1H antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1210 - HEK293 Cell Lysate

Concentration

1 mg/mL

Buffer

CACNA1H antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CACNA1H antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

CACNA1H antibody is human, mouse and rat reactive. Multiple isoforms of CACNA1H are known to exist.

Symbol

CACNA1H

NCBI Official Name

Calcium channel, voltage-dependent, T type, alpha 1H subunit

NCBI Organism

Homo sapiens

Background Reference 01

Cribbs LL, Lee JH, Yang J, et al. Cloning and characterization of alpha1H from human heart, a member of the T-type CA2+ channel gene family. Circ. Res. 1998; 83:103-9.

Background Reference 02

Sekiguchi F and Kawabata A. T-type calcium channels: functional regulation and implication in pain signaling. J. Pharmacol. Sci. 2013; 122:244-50.

Background Reference 03

McGivern JG. Targeting N-type and T-type calcium channels for the treatment of pain. Drug Discov. Today 2006; 11:245-53.

Background Reference 04

Markandeya YS, Fahey JM, Pluteanu F, et al. Caveolin-3 regulates protein kinase A modulation of the Cav3.2 (a1H) T-type Ca2+ channels. J. Biol. Chem. 2011; 286:2433-2444.