Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CACNA1H Antibody

Product Specifications

Background

The calcium channel protein CACNA1H is a T-type member of the alpha-1 subunit family that is part of the voltage-dependent calcium channel complex which mediates the influx of calcium ions into the cell upon membrane polarization (1,2) . CACNA1H is a subunit of Cav3.2 T-type calcium channel that is involved in neurological disorders such as epilepsy and pain (2,3) . CACNA1H associates with the caveolin protein Cav-3 and it is thought that Cav-3 regulates the Protein Kinase A (PKA) modulation of CACNA1H-containing Cav3.2 T-type calcium channels (4) .

NCBI Gene ID

8912

Swiss Prot

O95180

Accession Number

NP_066921

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

CACNA1H antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1210 - HEK293 Cell Lysate

Concentration

1 mg/mL

Buffer

CACNA1H antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CACNA1H antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=8029

Fragment

IgG

Specificity

CACNA1H antibody is human, mouse and rat reactive. Multiple isoforms of CACNA1H are known to exist.

Symbol

CACNA1H

NCBI Official Name

Calcium channel, voltage-dependent, T type, alpha 1H subunit

NCBI Organism

Homo sapiens

Background Reference 01

Cribbs LL, Lee JH, Yang J, et al. Cloning and characterization of alpha1H from human heart, a member of the T-type CA2+ channel gene family. Circ. Res. 1998; 83:103-9.

Background Reference 02

Sekiguchi F and Kawabata A. T-type calcium channels: functional regulation and implication in pain signaling. J. Pharmacol. Sci. 2013; 122:244-50.

Background Reference 03

McGivern JG. Targeting N-type and T-type calcium channels for the treatment of pain. Drug Discov. Today 2006; 11:245-53.

Background Reference 04

Markandeya YS, Fahey JM, Pluteanu F, et al. Caveolin-3 regulates protein kinase A modulation of the Cav3.2 (a1H) T-type Ca2+ channels. J. Biol. Chem. 2011; 286:2433-2444.

Other Product Names

Calcium channel voltage-dependent T type alpha 1H subunit, CACNA1HB, Cav3.2, ECA6, EIG6

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

53832009

Physical Properties

Liquid

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human PDLIM1 Interacting Kinase 1 Like (PDIK1L) ELISA Kit
MBS109614-01 48 Well

Human PDLIM1 Interacting Kinase 1 Like (PDIK1L) ELISA Kit

Ask
View Details
Human PDLIM1 Interacting Kinase 1 Like (PDIK1L) ELISA Kit
MBS109614-02 96 Well

Human PDLIM1 Interacting Kinase 1 Like (PDIK1L) ELISA Kit

Ask
View Details
Human PDLIM1 Interacting Kinase 1 Like (PDIK1L) ELISA Kit
MBS109614-03 5x 96 Well

Human PDLIM1 Interacting Kinase 1 Like (PDIK1L) ELISA Kit

Ask
View Details
Human PDLIM1 Interacting Kinase 1 Like (PDIK1L) ELISA Kit
MBS109614-04 10x 96 Well

Human PDLIM1 Interacting Kinase 1 Like (PDIK1L) ELISA Kit

Ask
View Details
NTMT2 (NM_001136107) Human Over-expression Lysate
LY427801 100 µg

NTMT2 (NM_001136107) Human Over-expression Lysate

Ask
View Details
Recombinant Synechococcus sp. Iron stress-induced chlorophyll-binding protein (isiA)
MBS7017543-01 0.02 mg

Recombinant Synechococcus sp. Iron stress-induced chlorophyll-binding protein (isiA)

Ask
View Details