What is the catalog number for GPRASP1 Antibody?

The catalog number for GPRASP1 Antibody is 7987.

What sizes are available for GPRASP1 Antibody?

GPRASP1 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does GPRASP1 Antibody come in?

GPRASP1 Antibody is available in 2 different pack sizes.

Is GPRASP1 Antibody in stock?

GPRASP1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

GPRASP1 Antibody

Product Specifications

Background

The G protein-coupled receptor associated sorting protein 1 (GPRASP1) is a member of the GPRASP family and is thought to modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors (1,2) . GPRASP1 interacts with receptors such as the D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CNR1) and targets these proteins for degradation in lysosomes (2) . Recently, it has been shown that increased GPRASP1 levels may act as a potential biomarker for breast cancer (3) .

NCBI Gene ID

9737

Swiss Prot

Q5JY77

Accession Number

NP_001171656

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

GPRASP1 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1288 - A20 Cell Lysate

Concentration

1 mg/mL

Buffer

GPRASP1 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

GPRASP1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

GPRASP1 antibody is human and mouse reactive. This antibody is predicted to not cross-react with GPRASP2.

Symbol

GPRASP1

NCBI Official Name

G protein-coupled receptor associated sorting protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Simonin F, Karcher P, Boeuf JJ, et al. Identification of a novel family of G protein-coupled receptor associated proteins. J. Neurochem. 2004; 89:766-75.

Background Reference 02

Moser E, Kargl J, Whistler JL, et al. G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning G protein-coupled receptors. Pharmacology 2010; 86:22-9.

Background Reference 03

Tuszynski GP, Rothman VL, Zheng X, et al. G-protein coupled receptor-associated sorting protein 1 (GASP-1), a potential biomarker in breast cancer. Exp. Mol. Pathol. 2011; 91:608-13.