What is the catalog number for XKR8 Antibody?

The catalog number for XKR8 Antibody is 7965.

What sizes are available for XKR8 Antibody?

XKR8 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does XKR8 Antibody come in?

XKR8 Antibody is available in 2 different pack sizes.

Is XKR8 Antibody in stock?

XKR8 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

XKR8 Antibody

Product Specifications

Background

The XK Kell blood group complex subunit-related family member 8 (XKR8) is a member of a family of proteins that promote the phagocytosis of dying cells by altering the phospholipid distribution of the plasma membrane (1) . XKR8 is thought to be a “scramblase”, an enzyme that eliminates the asymmetry of phospholipid distribution in the plasma membrane. In apoptotic cells, XKR8 promotes the cell-surface exposure of phosphatidylserine (PtdSer) which serves as a signal for phagocytosis (1,2) .

NCBI Gene ID

55113

Swiss Prot

Q9H6D3

Accession Number

NP_060523

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis

Purification

XKR8 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1319 - Human Stomach Tissue Lysate

Concentration

1 mg/mL

Buffer

XKR8 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

XKR8 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

XKR8 antibody is human reactive. At least two isoforms are known to exist; this antibody will detect both isoforms.

Symbol

XKR8

Positive Control 2

Cat. No. 10-801 - Human Stomach Tissue Slide

NCBI Official Name

XK, Kell blood group complex subunit-related family, member 8

NCBI Organism

Homo sapiens

Background Reference 01

Suzuki J, Denning DP, Imanishi E, et al. Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells. Science 2013; 341:403-6.

Background Reference 02

Wang X, Wu YC, Fadok VA, et al. Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12. Science 2003; 302:1563-6.