TICRR Antibody

Product Specifications

Background

TopBP1-interacting checkpoint and replication regulator, Treslin, chromosome 15 open reading frame 42, C15ORF42

NCBI Gene ID

90381

Swiss Prot

Q7Z2Z1

Accession Number

NP_689472

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

TICRR antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1308 - Human Small Intestine Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Mouse: (74%)

Buffer

TICRR antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TICRR antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

TICRR antibody is human specific. At least two isoforms of TICRR are known to exist.

Symbol

TICRR

Positive Control 2

Cat. No. 11-801 - Human Small Intestine Tissue Slide

NCBI Official Name

TOPBP1-interacting checkpoint and replication regulator

NCBI Organism

Homo sapiens

Background Reference 01

Sansam CL, Cruz NM, Danielian PS, et al. A vertebrate gene, ticrr, is an essential checkpoint and replication regulator. Genes Dev. 2010; 24:183-94.

Background Reference 02

Kumagai A, Shevchenko A, Shevchenko A, et al. Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. J. Cell Biol. 2011;193:995-1007.

Background Reference 03

Kumagai A, Shevchenko A, Shevchenko A, et al. Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. Cell 2010; 140:349-59.