What is the catalog number for POU2F3 Antibody?

The catalog number for POU2F3 Antibody is 7795.

What sizes are available for POU2F3 Antibody?

POU2F3 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does POU2F3 Antibody come in?

POU2F3 Antibody is available in 2 different pack sizes.

Is POU2F3 Antibody in stock?

POU2F3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

POU2F3 Antibody

Product Specifications

Background

POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1) . POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2) . It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3) . POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4) .

NCBI Gene ID

25833

Swiss Prot

Q9UKI9

Accession Number

NP_001231611

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

POU2F3 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1220 - SK-N-SH Cell Lysate

Concentration

1 mg/mL

Buffer

POU2F3 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

POU2F3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

POU2F3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist. This antibody will recognize both isoforms. POU2F3 antibody is predicted to not cross-react with other members of the POU domain class 2 family.

Symbol

POU2F3

NCBI Official Name

POU class 2 homeobox 3

NCBI Organism

Homo sapiens

Background Reference 01

Yukawa K, Yasui T, Yamamoto A, et al. Epoc-1: a POU-domain gene expressed in murine epidermal basal cells and thymic stromal cells. Gene 1993; 133:163-9.

Background Reference 02

Cabral A, Fischer DF, Vermeij WP, et al. Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation. J. Biol. Chem. 2003; 278:17792-9.

Background Reference 03

Matsumoto I, Ohmoto M, Narukawa M, et al. Skn-1a/Pou2f3 specifies taste receptor cell lineage. Nat. Neurosci. 2011; 14:685-7.

Background Reference 04

Zhang Z, Huettner PC, Nguyen L, et al. Aberrant promoter methylation and silencing of the POU2F3 gene in cervical cancer. Oncogene 2006; 25:5436-45.

Other Product Names

POU2F3 Antibody: PLA1, OCT11, PLA-1, Epoc-1, OCT-11, OTF-11, Skn-1a, OTF11, PLA1, POU domain, class 2, transcription factor 3, Octamer-binding protein 11, 41923