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PROM1 Antibody

Product Specifications

Background

PROM1 is a pentaspan transmembrane glycoprotein that localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation (1) . Mutations in this gene have been shown to result in retinitis pigmentosa (2) . Expression of this gene is also associated with several types of cancer (3) .

NCBI Gene ID

8842

Swiss Prot

O43490

Accession Number

NP_006008

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell, Cancer

Purification

PROM1 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

1 mg/mL

Buffer

PROM1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

PROM1 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=7783

Fragment

IgG

Specificity

PROM1 antibody is human, mouse and rat reactive. Multiple isoforms of PROM1 are known to exist.

Symbol

PROM1

Positive Control 2

Cat. No. 17-005 - Jurkat Cell Slide

NCBI Official Name

Prominin 1

NCBI Organism

Homo sapiens

Background Reference 01

Yin AH, Miraglia S, Zanjani ED, et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 1997; 90:5002-12.

Background Reference 02

Zhang Q, Zulfiqar F, Xiao X, et al. Severe retinitis pigmentosa mapped to 4p15 and associated with a novel mutation in the PROM1 gene. Hum. Genet. 2007; 122:293-9.

Background Reference 03

Tabu K, Bizen N, Taga T, et al. Gene regulation of Prominin-1 (CD133) in normal and cancerous tissues. Adv. Exp. Med. Biol. 2013; 777:73-85.

Other Product Names

PROM1 Antibody: RP41, AC133, CD133, MCDR2, STGD4, CORD12, PROML1, MSTP061, Prominin-1, Antigen AC133

Tested Applications

ELISA, WB, ICC, IF

Protein ID

5174387

Physical Properties

Liquid

Available Sizes

Curated Selection

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