Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

MIB1 Antibody

Product Specifications

Background

The E3 ubiquitin-protein ligase MIB1, also known as Mindbomb homolog 1, contains multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase (1) . MIB1 interacts with and regulates the cellular expression of the death-associated protein kinase 1 (DAPK1) protein by promoting its ubiquitination and degradation (1) . It also positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis (2) .

NCBI Gene ID

57534

Swiss Prot

Q86YT6

Accession Number

NP_065825

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis, Apoptosis

Purification

MIB1 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1202 - A431 Cell Lysate

Concentration

1 mg/mL

Buffer

MIB1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

MIB1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=7781

Fragment

IgG

Specificity

MIB1 antibody is human, mouse and rat reactive. At least three isoforms of MIB1 are known to exist.

Symbol

MIB1

Positive Control 2

Cat. No. 17-002 - A-431 Cell Slide

NCBI Official Name

Mindbomb E3 ubiquitin protein ligase 1

NCBI Organism

Homo sapiens

Background Reference 01

Jin Y, Blue EK, Dixon S, et al. A death-associated protein kinase (DAPK) -interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular level of DAPK. J. Biol. Chem. 2002; 277:46980-6.

Background Reference 02

Hansson EM, Lanner F, Das D, et al. Control of Notch0ligand endocytosis by ligand-receptor interaction. J. Cell Sci. 2010; 123:2931-42.

Other Product Names

MIB1 Antibody: MIB, DIP1, ZZZ6, DIP-1, LVNC7, ZZANK2, KIAA1323, E3 ubiquitin-protein ligase MIB1, DAPK-interacting protein 1

Tested Applications

ELISA, WB, ICC, IF

Protein ID

30348954

Physical Properties

Liquid

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Trk A (phospho Tyr757) Polyclonal Antibody
E44H00284 100ul

Trk A (phospho Tyr757) Polyclonal Antibody

Ask
View Details
Mouse Sumo3 activation kit by CRISPRa
GA203995 1 Kit

Mouse Sumo3 activation kit by CRISPRa

Ask
View Details
MIR4459 Human qPCR Template Standard (MI0016805)
HK300972 200 Reactions

MIR4459 Human qPCR Template Standard (MI0016805)

Ask
View Details
Tβ-10 siRNA (m)
sc-63095 10 µM

Tβ-10 siRNA (m)

Ask
View Details