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UBIAD1 Antibody

Product Specifications

Background

The UbiA prenyltransferase domain containing 1 (UBIAD1) protein , also known as TERE1, was initially identified as a down-regulated gene in transitional cell carcinoma of the bladder (1) . Recently it has been shown to bind the cholesterol carrier APOE and modulate cellular cholesterol levels (2) . Mutations in the UBIAD1 gene can cause Schnyder crystalline corneal dystrophy, an autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids (3) .

NCBI Gene ID

29914

Swiss Prot

Q9Y5Z9

Accession Number

NP_037451

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

UBIAD1 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1404 - Mouse Liver Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Chicken: (87%)

Buffer

UBIAD1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

UBIAD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=7751

Fragment

IgG

Specificity

UBIAD1 antibody is human, mouse and rat reactive.

Symbol

UBIAD1

NCBI Official Name

UbiA prenyltransferase domain containing 1

NCBI Organism

Homo sapiens

Background Reference 01

McGarvey TW, Nguyen T, Tomaszewski JE, et al. Isolation and characterization of TERE1 gene, a gene down-regulated in transitional cell carcinoma of the bladder. Oncogene 2001; 20:1042-51.

Background Reference 02

Fredericks WJ, McGarvey T, Wang H, et al. The bladder tumor suppressor protein TERE1 (UBIAD1) modulates cell cholesterol: implications for tumor progression. DNA Cell Biol. 2011; 30:851-64.

Background Reference 03

Orr A, Dube MP, Marcadier J, et al. Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy. PLoS One 2007; 2:e685.

Other Product Names

UBIAD1 Antibody: SCCD, TERE1, UbiA prenyltransferase domain-containing protein 1, Transitional epithelial response protein 1

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

7019551

Physical Properties

Liquid

Available Sizes

Curated Selection

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