Hantaan Virus Nucleocapsid Antibody

Product Specifications

Background

Hantaan virus (HNTV) is the prototype virus of the genus hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA virus that is the eiological agent of Korean hemorrhagic fever (1) . Infection of cultured Vero E6 cells with HNTV induced expression of the heat shock protein HSP70. A substantial fraction of HSP70 was found to be associated with the HNTV nucleocapsid (NP) (2) . Vero E6 cells that overexpress HSP70 show significantly reduced levels of NP and an increased resistance to infection by HNTV (2) .

NCBI Gene ID

2943078

Swiss Prot

P05133

Accession Number

AFA36178

Host

Rabbit

Reactivity

Virus

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease

Purification

Hantaan virus nucleocapsid antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Buffer

Hantaan virus nucleocapsid antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Hantaan virus nucleocapsid antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Applications Notes

Hantaan virus nucleocapsid antibody can detect 10ng Hantaan virus nucleocapsid peptide in ELISA at 1 μ g/ml.

Symbol

HTNVsSgp1

NCBI Official Name

HTNVsSgp1 nucleocapsid protein

NCBI Organism

Hantaan virus

Background Reference 01

Arikawa J, Lapenotiere HF, Iacono-Connors L, et al. Coding properties of the S and M genome segments of Sapporo rat virus: comparison to other causative agents of hemorrhagic fever with renal syndrome. Virology 1990; 176:114-25.

Background Reference 02

Yu L, Ye L, Zhao R, et al. HSP70 induced by Hantavirus intfection interacts with viral nucleocapsid protein and its overexpression suppresses virus infection in Vero E6 cells. Am. J. Transl. Res. 2009; 1:367-80.