Sin Nombre Virus Glycoprotein 2 Antibody
Product Specifications
Background
Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1) . Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc) . While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2), no such degradation was observed for the G2 glycoprotein.
NCBI Gene ID
2654026
Swiss Prot
Q89905
Accession Number
NP_941974
Host
Rabbit
Reactivity
Virus
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Infectious Disease
Purification
Sin Nombre virus glycoprotein 2 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Buffer
Sin Nombre virus glycoprotein 2 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Sin Nombre Glycoprotein 2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Applications Notes
Sin Nombre virus glycoprotein 2 antibody can detect 10ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μ g/ml.
Symbol
SNVsMgp1
NCBI Official Name
SNVsMgp1 glycoprotein precursor
NCBI Organism
Sin Nombre virus
Background Reference 01
Spiropoulou CF, Morzunov S, Feldmann H, et al. Genome structure and variability of a virus causing hantavirus pulmonary syndrome. Virology 1994; 200:715-23.
Background Reference 02
Hussein ITM, Cheng E, Ganaie SS, et al. Autophagic clearance of Sin Nombre hanatavirus glycoprotein Gn promotes virus replication in cells. J. Virol. 2012; 86:7520-9.
Other Product Names
Sin Nombre Virus Glycoprotein 2 Antibody:
Tested Applications
ELISA
Protein ID
38371724
Physical Properties
Liquid
Available Sizes
Frequently Asked Questions
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