Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CXCR3 Antibody

Product Specifications

Background

The CXCR3 protein is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-gamma), CXCL10/IP10 (interferon-gamma-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell alpha-chemoattractant) (reviewed in 1) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration (2) . Similar to other chemokine receptors such as CXCR4, CXCR3 has been implicated in several malignancies as a biomarker of tumor behavior as well as a potential therapeutic target (3) .

NCBI Gene ID

2833

Swiss Prot

P49682

Accession Number

NP_001136269

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Chemokines & Cytokines

Purification

CXCR3 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Goat: (89%), Bovine: (88%)

Buffer

CXCR3 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CXCR3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=7647

Fragment

IgG

Specificity

CXCR3 antibody is human, mouse and rat reactive. At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms.

Symbol

CXCR3

Positive Control 2

Cat. No. 17-011 - Hep G2 Cell Slide

NCBI Official Name

Chemokine (C-X-C motif) receptor 3

NCBI Organism

Homo sapiens

Background Reference 01

Groom JR and Luster AD. CXCR3 ligands: redundant, collaborative and antagonistic functions. Immunol. Cell Biol. 2011; 89:207-15.

Background Reference 02

Maghazachi AA. Role of chemokines in the biology of natural killer cells. Curr. Top Microbiol. Immunol. 2010; 341:37-58.

Background Reference 03

Fulton AM. The chemokine receptors CXCR4 and CXCR3 in cancer. Curr. Oncol. Rep. 2009; 11:125-31.

Other Product Names

CXCR3 Antibody: GPR9, MigR, CD182, CD183, Mig-R, CKR-L2, CMKAR3, IP10-R, GPR9, C-X-C chemokine receptor type 3, CXC-R3

Tested Applications

ELISA, WB, ICC, IF

Protein ID

218563730

Physical Properties

Liquid

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Triethylenephosphoramide-d12
TRC-T776602-1MG 1 mg

Triethylenephosphoramide-d12

Ask
View Details
Tmem129-set siRNA/shRNA/RNAi Lentivector (Mouse)
46884094 4 x 500 ng

Tmem129-set siRNA/shRNA/RNAi Lentivector (Mouse)

Ask
View Details
LGR5 Mouse Monoclonal Antibody [Clone ID: UMLBI212]
E45M21948 100 ug

LGR5 Mouse Monoclonal Antibody [Clone ID: UMLBI212]

Ask
View Details
Human CYB5R1 Protein, His Tag
E40KMPH4249 20ug

Human CYB5R1 Protein, His Tag

Ask
View Details
GPR50 (D1D6I) Rabbit Monoclonal Antibody
CST 14032T 20 µL

GPR50 (D1D6I) Rabbit Monoclonal Antibody

Ask
View Details
Rab 36 Lentiviral Activation Particles (m)
sc-429444-LAC 200 µL

Rab 36 Lentiviral Activation Particles (m)

Ask
View Details