What is the catalog number for CXCR3 Antibody?

The catalog number for CXCR3 Antibody is 7647.

What sizes are available for CXCR3 Antibody?

CXCR3 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does CXCR3 Antibody come in?

CXCR3 Antibody is available in 2 different pack sizes.

Is CXCR3 Antibody in stock?

CXCR3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

CXCR3 Antibody

Product Specifications

Background

The CXCR3 protein is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-gamma), CXCL10/IP10 (interferon-gamma-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell alpha-chemoattractant) (reviewed in 1) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration (2) . Similar to other chemokine receptors such as CXCR4, CXCR3 has been implicated in several malignancies as a biomarker of tumor behavior as well as a potential therapeutic target (3) .

NCBI Gene ID

2833

Swiss Prot

P49682

Accession Number

NP_001136269

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Chemokines & Cytokines

Purification

CXCR3 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Goat: (89%), Bovine: (88%)

Buffer

CXCR3 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CXCR3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

CXCR3 antibody is human, mouse and rat reactive. At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms.

Symbol

CXCR3

Positive Control 2

Cat. No. 17-011 - Hep G2 Cell Slide

NCBI Official Name

Chemokine (C-X-C motif) receptor 3

NCBI Organism

Homo sapiens

Background Reference 01

Groom JR and Luster AD. CXCR3 ligands: redundant, collaborative and antagonistic functions. Immunol. Cell Biol. 2011; 89:207-15.

Background Reference 02

Maghazachi AA. Role of chemokines in the biology of natural killer cells. Curr. Top Microbiol. Immunol. 2010; 341:37-58.

Background Reference 03

Fulton AM. The chemokine receptors CXCR4 and CXCR3 in cancer. Curr. Oncol. Rep. 2009; 11:125-31.

Other Product Names

CXCR3 Antibody: GPR9, MigR, CD182, CD183, Mig-R, CKR-L2, CMKAR3, IP10-R, GPR9, C-X-C chemokine receptor type 3, CXC-R3

Tested Applications

ELISA, WB, ICC, IF

Protein ID

218563730

Physical Properties

Liquid

Available Sizes

Frequently Asked Questions

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