What is the catalog number for IL-22 Antibody?

The catalog number for IL-22 Antibody is 7593.

What sizes are available for IL-22 Antibody?

IL-22 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does IL-22 Antibody come in?

IL-22 Antibody is available in 2 different pack sizes.

Is IL-22 Antibody in stock?

IL-22 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

IL-22 Antibody

Product Specifications

Background

Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation (1) . Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells (2) . IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles (3) .

NCBI Gene ID

50616

Swiss Prot

Q9GZX6

Accession Number

NP_065386

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

IL-22 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1201 - HeLa Cell Lysate

Concentration

1 mg/mL

Buffer

IL-22 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

IL-22 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

IL-22 antibody is human, mouse, and rat reactive. Multiple isoforms of IL-22 are known to exist.

Symbol

IL22

Positive Control 2

Cat. No. 17-001 - HeLa Cell Slide

NCBI Official Name

Interleukin 22

NCBI Organism

Homo sapiens

Background Reference 01

Xie MH, Aggarwal S, Ho WH, et al. Interleukin (IL) -22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 2000; 275:31335-9.

Background Reference 02

Wolk K, Kunz S, Witte E, et al. IL-22 increases the innate immunity of tissues. Immunity 2004; 21:241-54.

Background Reference 03

Wolk K, Witte E, Wallace E, et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol. 36:1309-23.