LRRC26 Antibody

Product Specifications

Background

The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues (1) . LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis (2) . LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels (3) .

NCBI Gene ID

389816

Swiss Prot

Q2I0M4

Accession Number

NP_001013675

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

LRRC26 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1312 - Human Prostate Tissue Lysate

Concentration

1 mg/mL

Buffer

LRRC26 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

LRRC26 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

LRRC26 antibody is human specific.

Symbol

LRRC26

Positive Control 2

Cat. No. 1205 - Jurkat Cell Lysate

NCBI Official Name

Leucine rich repeat containing 26

NCBI Organism

Homo sapiens

Background Reference 01

Egland KA, Liu XF, Squires S, et al. High expression of a cytokeratin-associated protein in many cancers. Proc. Natl. Acad. Sci. USA 2006; 103:5929-34.