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ADROPIN Antibody

Product Specifications

Background

ADROPIN is a recently identified protein that has been implicated in the maintenance of energy homeostasis and insulin resistance (1-3) . ADROPIN expression is regulated by energy status and dietary nutrient content and is altered by obesity and regulates the expression of hepatic lipogenic genes and adipose tissue peroxisome proliferator-activated receptor gamma (PPAR-gamma) (1) . ADROPIN levels increase with dietary fat content (2) . ADROPIN has also been proposed to play a role in the regulation of endothelial function (3) .

NCBI Gene ID

375704

Swiss Prot

Q6UWT2

Accession Number

NP_940975

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity

Purification

ADROPIN antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1303 - Human Brain Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (94%)

Buffer

ADROPIN antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

ADROPIN antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=7527

Fragment

IgG

Specificity

ADROPIN antibody is human, mouse and rat reactive. Despite its predicted molecular weight, ADROPIN often migrates at a higher than expected molecular weight in SDS-PAGE.

Symbol

ENHO

Positive Control 2

Cat. No. 10-301 - Human Brain Tissue Slide

NCBI Official Name

Energy homeostasis associated

NCBI Organism

Homo sapiens

Background Reference 01

Kumar KG, Trevaskis JL, Lam DD, et al. Identification of Adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism. Cell Metab. 2008; 8:468-81.

Background Reference 02

Kumar KG, Zhang J, Gao S, et al. Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity 2012; 1394-402.

Background Reference 03

Lovren F, Pan Y, Quan A, et al. Adropin is a novel regulator of endothelial function. Circulation 2010; 122:S185-92.

Other Product Names

ADROPIN Antibody: UNQ470, C9orf165, UNQ470/PRO830, Adropin, Energy homeostasis-associated protein

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

58218977

Physical Properties

Liquid

Available Sizes

Curated Selection

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