IL-9 Antibody

Product Specifications

Background

Interleukin 9 (IL-9) is a cytokine secreted by TH2 lymphocytes that acts as a regulator of a variety of hematopoietic cells, stimulates cell proliferation and prevents apoptosis (1,2) . It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins (3) . The IL-9 gene has been identified as a candidate gene for asthma (4) . Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness (5) .

NCBI Gene ID

3578

Swiss Prot

P15248

Accession Number

NP_000581

Host

Rabbit

Reactivity

Human

Immunogen

7495

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Recombinant Protein Test (Figure 2) : Anti-IL-9 antibodies (7495) detected human IL-9 recombinant protein at different concentrations. Recombinant Protein Test7495

Field of Research

Immunology

Purification

IL-9 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1306 - Human Spleen Tissue Lysate

Concentration

1 mg/mL

Buffer

IL-9 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

IL-9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

IL-9 antibody is human specific. IL-9 antibody is predicted to no cross-react with IL-7.

Isoform

Human IL-9 has one isoform (144aa, 16kD) . Mouse IL-9 has one isoform (144aa, 16kD) and Rat IL-9 also has one isoform (144aa, 16kD) . 7495 can detect human isoform, but cannot detect mouse and rat.

Symbol

IL9

Positive Control 2

Cat. No. 10-901 - Human Spleen Tissue Slide

Positive Control 3

Cat. No. 1201 - HeLa Cell Lysate

NCBI Official Name

Interleukin 9

NCBI Organism

Homo sapiens

Background Reference 01

Renauld et al. Cytokine 1990; 2:9-12.

Background Reference 02

Tete et al. J. Biol. Homeost. Agents 2012; 26:319-26.

Background Reference 03

Knoops and Renauld. Growth Factors 2004; 22:207-15.

Background Reference 04

Nicolaides et al. Proc. Natl. Acad. Sci. USA 1997; 94:13175-80.

Other Product Names

IL-9 Antibody : P40, HP40, IL-9, Interleukin-9, Cytokine P40

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

10834980

Physical Properties

Liquid

Available Sizes

Curated Selection

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