Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

IL-17RA Antibody

Product Specifications

Background

IL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1) . It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2) . IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4) . Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5) .

NCBI Gene ID

23765

Swiss Prot

Q96F46

Accession Number

NP_055154

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

IL-17RA Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1288 - A20 Cell Lysate

Concentration

1 mg/mL

Buffer

IL-17RA Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

IL-17RA antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

Other IL-17RA antibodies show similar size band

Fragment

IgG

Specificity

IL-17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits.

Symbol

IL17RA

Positive Control 2

Cat. No. 10-901 - Human Spleen Tissue Slide

NCBI Official Name

Interleukin 17 receptor A

NCBI Organism

Homo sapiens

Background Reference 01

Yao Z, Painter SL, Fanslow WC, et al. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 1995; 155: 5483-6.

Background Reference 02

Yao Z, Fanslow WC, Seldin MF, et al. Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 1995; 3:811-21.

Background Reference 03

Rickel EA, Siegel LA, Yoon BR, et al. Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J. Immunol. 2008;181:4299-310.

Background Reference 04

Wang M, Wang L, Ren T, et al. IL-17A/IL-17RA interaction promoted metastasis of osteosarcoma cells. Cancer Biol. Ther. 2012;14 (2) .

Other Product Names

IL-17RA Antibody: CD217, IL17R, CANDF5, CDw217, IL-17RA, hIL-17R, Interleukin-17 receptor A, IL-17 receptor A

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

23238208

Physical Properties

Liquid

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

TAF3 Peptide - middle region
orb2014120 100 µg

TAF3 Peptide - middle region

Sign In for Pricing
View Details
CC2D2A Rabbit Polyclonal Antibody
orb326553 100 µL

CC2D2A Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
SDCCAG33 Antibody Blocking peptide
orb1447279 500 µg

SDCCAG33 Antibody Blocking peptide

Sign In for Pricing
View Details
Guinea pig Omentin ELISA Kit
MBS731133-01 48 Well

Guinea pig Omentin ELISA Kit

Sign In for Pricing
View Details
Guinea pig Omentin ELISA Kit
MBS731133-02 96 Well

Guinea pig Omentin ELISA Kit

Sign In for Pricing
View Details
Guinea pig Omentin ELISA Kit
MBS731133-03 5x 96 Well

Guinea pig Omentin ELISA Kit

Sign In for Pricing
View Details