Rift Valley Fever Virus Polymerase Antibody

Product Specifications

Background

Rift Valley Fever Virus Polymerase Antibody: Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes (1) . During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever. The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity (2) . The three segments are referred to as the L, M, and S segments. The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively. The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins (3) .

NCBI Gene ID

9538294

Swiss Prot

A2SZS2

Accession Number

ABD51508

Host

Rabbit

Reactivity

Virus

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease

Purification

Rift Valley Fever Virus Polymerase Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Buffer

RVF virus Polymerase Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Rift Valley Fever Virus Polymerase antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Calculated Molecular Weight

Predicted: 230 kDa

Fragment

IgG

Applications Notes

RVF virus Polymerase antibody can detect 10 ng RVF virus Polymerase peptide in ELISA at 1 μ g/mL.

Symbol

RVFV_sL_gp1

NCBI Official Name

RVFV_sL_gp1 polymerase [ Rift Valley fever virus ]

NCBI Organism

Rift Valley fever virus

Background Reference 01

Morrill JC and McClain DJ. Epidemiology and pathogenesis of the Rift Valley fever and other phleboviruses, p. 281-93 in H Fraenkel-Conrat and RR Wagner (ed.) The viruses. Plenum Press, New York, NY.

Background Reference 02

Schmaljohn C and Hooper JW. Bunyaviridae: the viruses and their replication, 4th ed. Lippincott Williams & Wilkins, Philadelphia, PA.

Background Reference 03

Giorgi C, Accardi L, Nicoletti M, et al. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian sandfly fever, and Uukuniemi viruses. Virology 1991; 180:738-53.