FOXA2 Antibody

Product Specifications

Background

FOXA2 Antibody: FOXA2 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. FOXA2 was initially identified through library screening as a closely related homolog of FOXA1. Both FOXA2 and FOXA1 act as transcriptional activators in adult liver and also play a role in body axis formation, neural tube patterning and definitive endoderm formation during gastrulation.

NCBI Gene ID

3170

Swiss Prot

Q9Y261

Accession Number

NP_068556

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

FOXA2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1310 - Human Bladder Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Rat: (94%), Mouse: (94%)

Buffer

FOXA2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

FOXA2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

At least two isoforms of FOXA2 are known to exist; this antibody will detect both isoforms. FOXA2 antibody is predicted to not cross-react with other members of the FOXA protein family.

Symbol

FOXA2

NCBI Official Name

Forkhead box A2

NCBI Organism

Homo sapiens

Background Reference 01

Hannenhalli S and Kaestner KH. The evolution of Fox genes and their role in development and disease. Nat. Rev. Genet. 2009; 10:233-40.

Background Reference 02

Lai E, Prezioso VR, Tao WF, et al. Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Genes Dev. 1991; 5:416-27.

Background Reference 03

Sasaki H and Hogn BL. Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Dev. 1993; 118:47-59.