What is the catalog number for CCL17 Antibody?

The catalog number for CCL17 Antibody is 7239.

What sizes are available for CCL17 Antibody?

CCL17 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does CCL17 Antibody come in?

CCL17 Antibody is available in 2 different pack sizes.

Is CCL17 Antibody in stock?

CCL17 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

CCL17 Antibody

Product Specifications

Background

CCL17 Antibody: CCL17, also known as TARC, binds to chemokine receptors CCR4 and CCR8 and plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is secreted from monocyte-derived DCs and endothelial cells and is responsible for selective recruitment and migration of activated Th2 lymphocytes. CCL17 is also required for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells under inflammatory conditions.

NCBI Gene ID

6361

Swiss Prot

Q92583

Accession Number

NP_002978

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

CCL17 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1466 - Rat Spleen Tissue Lysate

Concentration

1 mg/mL

Buffer

CCL17 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CCL17 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Calculated Molecular Weight

10 kDa

Fragment

IgG

Symbol

CCL17

Positive Control 2

Cat. No. 10-901 - Human Spleen Tissue Slide

NCBI Official Name

Chemokine (C-C motif) ligand 17

NCBI Organism

Homo sapiens

Background Reference 01

Imai T, Baba M, Nishimura M, et al. The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J. Biol. Chem. 1997; 272:15036-42.

Background Reference 02

Bernardini G, Hedrick J, Sozzani S, et al. Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. Eur. J. Immunol. 1998; 28:582-8.

Background Reference 03

Alferink J, Lieberam I, Reindl W, et al. Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J. Exp. Med. 2003; 197:585-99.

Background Reference 04

Stutte S, Quast T, Gerbitzki N, et al. Requirement of CCL17 for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells. Proc. Natl. Acad. Sci. USA 2010; 107:8736-41.