What is the catalog number for IL-15RA Antibody?

The catalog number for IL-15RA Antibody is 7233.

What sizes are available for IL-15RA Antibody?

IL-15RA Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does IL-15RA Antibody come in?

IL-15RA Antibody is available in 2 different pack sizes.

Is IL-15RA Antibody in stock?

IL-15RA Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

IL-15RA Antibody

Product Specifications

Background

IL-15RA Antibody: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.

NCBI Gene ID

3601

Swiss Prot

Q13261

Accession Number

NP_001243694

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

IL-15RA Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1468 - Rat Small Intestine Tissue Lysate

Concentration

1 mg/mL

Buffer

IL-15RA Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

IL-15RA antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

Multiple isoforms of IL-15RA are known to exist.

Symbol

IL15RA

NCBI Official Name

Interleukin 15 receptor, alpha

NCBI Organism

Homo sapiens

Background Reference 01

Giri JG, Kumaki S, Ahdieh M, et al. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J. 1995; 14:3654-63.

Background Reference 02

Bodnar A, Nizsaloczki E, Mocsar G, et al. A biophysical approach to IL-2 and IL-15 receptor function: localization, conformation and interactions. Immunol. Lett. 2008; 116:117-25.

Background Reference 03

Lorenz HM, Hieronymus T, Grunke M, et al. Differential role for IL-2 and IL-15 in the inhibition of apoptosis in short-term activated human lymphocytes. Scand. J. Immunol. 1997; 45:660-9.