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TRPV1 Antibody

Product Specifications

Background

TRPV1 Antibody: TRPV1 is a receptor for capsaicin, the main pungent ingredient in hot chili peppers, and elicits a sensation of burning pain by selectively activating sensory neurons. TRPV1 is a non-selective cation channel that is structurally related to members of the TRP family of ion channels such as TRPC3 and TRPC6. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.

NCBI Gene ID

7442

Swiss Prot

Q8NER1

Accession Number

NP_542437

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

TRPV1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1204 - K562 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Guinea pig: (81%), Mouse: (75%)

Buffer

TRPV1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TRPV1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=7179

Calculated Molecular Weight

Predicted: 92 kDa

Fragment

IgG

Symbol

TRPV1

NCBI Official Name

Transient receptor potential cation channel, subfamily V, member 1

NCBI Organism

Homo sapiens

Background Reference 01

Eid SR and Cortright DN. Transient receptor potential channels on sensory nerves. Handb. Exp. Pharmacol. 2009; 194:261-81.

Background Reference 02

Minke B and Cook B. TRP channel proteins and signal transduction. Physiol. Rev. 2002; 82:429-72.

Background Reference 03

Planells-Cases R, Valente P, Ferrer-Montiel A, et al. Complex regulation of TRPV1 and related thermo-TRPs: implications for therapeutic intervention. Adv. Exp. Med. Biol. 2011; 704:491-515.

Other Product Names

TRPV1 Antibody: VR1, VR1, Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, TrpV1

Tested Applications

ELISA, WB

Protein ID

74315354

Physical Properties

Liquid

Available Sizes

Curated Selection

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