What is the catalog number for MECR Antibody?

The catalog number for MECR Antibody is 7151.

What sizes are available for MECR Antibody?

MECR Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does MECR Antibody come in?

MECR Antibody is available in 2 different pack sizes.

Is MECR Antibody in stock?

MECR Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

MECR Antibody

Product Specifications

Background

MECR Antibody: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.

NCBI Gene ID

51102

Swiss Prot

Q9BV79

Accession Number

NP_057095

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

MECR Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1303 - Human Brain Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Buffer

MECR Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

MECR antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Calculated Molecular Weight

Predicted: 41 kDa

Fragment

IgG

Specificity

At least two isoforms of MECR are known to exist; this antibody will detect both isoforms.

Symbol

MECR

Positive Control 2

Cat. No. 1403 - Mouse Brain Tissue Lysate

Positive Control 3

Cat. No. 1463 - Rat Brain Tissue Lysate

NCBI Official Name

Mitochondrial trans-2-enoyl-CoA reductase

NCBI Organism

Homo sapiens

Background Reference 01

Masuda N, Yasumo H, Furusawa T, et al. Nuclear receptor binding factor-1 (NRBF-1), a protein interacting with a wide spectrum of nuclear hormone receptors. Gene 1998; 221:225-33.

Background Reference 02

Chen Z, Leskinen H, Liimatta E, et al. Myocardial overexpression of Mecr, a gene of mitochondrial FAS II leads to cardiac dysfunction in mouse. PLoS One 2009; 4:e5589.