What is the catalog number for GRINA Antibody?

The catalog number for GRINA Antibody is 7147.

What sizes are available for GRINA Antibody?

GRINA Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does GRINA Antibody come in?

GRINA Antibody is available in 2 different pack sizes.

Is GRINA Antibody in stock?

GRINA Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

GRINA Antibody

Product Specifications

Background

GRINA Antibody: The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein) . They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.

NCBI Gene ID

2907

Swiss Prot

Q7Z429

Accession Number

NP_001009184

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis

Purification

GRINA Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1313 - Human Testis Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Mouse: (94%), Rat: (94%), Bovine: (83%)

Buffer

GRINA Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

GRINA antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Calculated Molecular Weight

Predicted: 41 kDa

Fragment

IgG

Specificity

GRINA antibody is predicted to not cross-react with other members of the TMBIM family.

Symbol

GRINA

NCBI Official Name

Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

NCBI Organism

Homo sapiens

Background Reference 01

Yamaji T, Nishikawa K and Hanada K et al. Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis. J. Biol. Chem. 2010; 285:35505-18.

Background Reference 02

Nielsen JA, Chambers MA, Romm E, et al. Mouse transmembrane BAX inhibitor motif 3 (Tmbim3) encodes a 38 kDa transmembrane protein expressed in the central nervous system. Mol. Cell. Biochem. 2011; 357:73-81.

Background Reference 03

Rojas-Rivera D, Armisén R, Colombo A, et al. TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis. Cell Death Differ. 2012; 19:1013-26.