GDF1 Antibody

Product Specifications

Background

GDF1 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.

NCBI Gene ID

2657

Swiss Prot

P27539

Accession Number

NP_001483

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

GDF1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1462 - Rat Lung Tissue Lysate

Concentration

1 mg/mL

Buffer

GDF1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

GDF1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

IgG

Specificity

GDF1 antibody is predicted to not cross-react with any other members of the growth differentiation factor family.

Symbol

GDF1

Positive Control 2

Cat. No. 10-101 - Human Lung Tissue Slide

NCBI Official Name

Growth differentiation factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Massague J. 1990. The transforming growth factor-beta family. Ann. Rev. Cell Biol. 6:597-641.

Background Reference 02

Lee SJ. Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure. Proc. Natl. Acad. Sci. USA 1991; 88:4250-4.