TNFAIP2 Antibody

Product Specifications

Background

TNFAIP2 Antibody: TNFAIP2, also known as B94, is a TNF-a-regulated gene that is expressed in endothelial cells, peripheral blood cells, and mature sperm. Recently, elevated TNFAIP2 expression was observed in nasopharyngeal carcinoma, and high expression of TNFAIP2 was significantly correlated with higher levels of cell migration, invasion and metastasis, suggesting that TNFAIP2 may serve as a useful prognostic indicator for nasopharyngeal carcinoma. TNFAIP2 has also been implicated as part of the viral-sensing circuit of the innate immune response.

NCBI Gene ID

7127

Swiss Prot

Q03169

Accession Number

NP_006282

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

TNFAIP2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1204 - K562 Cell Lysate

Concentration

1 mg/mL

Buffer

TNFAIP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TNFAIP2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

72 kDa

Fragment

IgG

Specificity

At least two isoforms of TNFAIP2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with TNFAIP3.

Symbol

TNFAIP2

Positive Control 2

Cat. No. 17-004 - K-562 Cell Slide

NCBI Official Name

Tumor necrosis factor, alpha-induced protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Wolf FW, Sarma V, Deldin M, et al. B94, a primary response gene inducible by tumor necrosis factor-alpha, is expressed in developing hematopoietic cells and the sperm acrosome. J. Biol. Chem. 1994; 269:3633-40.

Background Reference 02

Chen LC, Chen CC, Liang Y, et al. A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma. Mod. Pathol. 2011; 24:175-84.