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DCP2 Antibody

Product Specifications

Background

DCP2 Antibody: The removal, or decapping, of eukaryotic mRNA is an important step in the degradation of mRNA. Decapping protein 2 (DCP2) is the major mRNA decapping enzyme in cells. It is a member of the Nudix hydrolases superfamily of proteins that predominantly catalyze the hydrolysis of small nucleoside diphosphate substrates linked to another moiety. DCP2 is widely expressed in multiple tissues at varying levels, with highest expression seen in testis and brain.

NCBI Gene ID

167227

Swiss Prot

Q8IU60

Accession Number

NP_689837

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

DCP2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1210 - HEK293 Cell Lysate

Concentration

1 mg/mL

Buffer

DCP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

DCP2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=7049

Calculated Molecular Weight

46 kDa

Fragment

IgG

Specificity

Multiple isoforms of DCP2 are known to exist.

Symbol

DCP2

Positive Control 2

Cat. No. 11-701 - Human Testis Tissue Slide

NCBI Official Name

DCP2 decapping enzyme homolog (S. cerevisiae)

NCBI Organism

Homo sapiens

Background Reference 01

Song MG, Li Y, and Kiledjian M. Multiple mRNA decapping enzymes in mammalian cells. Mol. Cell 2010; 40:423-32.

Background Reference 02

Dunckley T and Parker R. The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif. EMBO J. 18:5411-22.

Background Reference 03

Bessman MJ, Frick DN, and O'Handley SF. The MutT proteins of “Nudix" hydrolases, a family of versatile, widely distributed, “housecleaning" enzymes. J. Biol. Chem. 1996; 271:25059-62

Other Product Names

DCP2 Antibody: NUDT20, NUDT20, m7GpppN-mRNA hydrolase, Nucleoside diphosphate-linked moiety X motif 20, Nudix motif 20

Tested Applications

ELISA, WB, IF

Protein ID

31542498

Physical Properties

Liquid

Available Sizes

Curated Selection

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