SGSM3 Antibody

Product Specifications

Background

SGSM3 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. Little is known of the exact function of SGSM3.

NCBI Gene ID

27352

Swiss Prot

Q96HU1

Accession Number

CAQ08933

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

SGSM3 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1210 - HEK293 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Rat: (82%), Mouse: (82%), Bovine: (79%)

Buffer

SGSM3 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SGSM3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

82 kDa

Fragment

IgG

Specificity

Multiple isoforms of SGSM3 are known to exist. SGSM3 antibody is predicted to not cross react with other SGSM family proteins.

Symbol

SGSM3

Positive Control 2

Cat. No. 17-010 - HEK293 Cell Slide

NCBI Official Name

Small G protein signaling modulator 3

NCBI Organism

Homo sapiens

Background Reference 01

Bar-Sagi D and Hall A. Ras and Rho GTPases: a family reunion. Cell 2000; 103:227-38.

Background Reference 02

Colicelli J. Human ras superfamily proteins and related GTPases. Sci. STKE 2004; 250:RE13.

Background Reference 03

Yang H, Sasaki T, Minoshima S, et al. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB) -mediated signaling pathway. Genomics 2007; 90:249-60.