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SHQ1 Antibody

Product Specifications

Background

SHQ1 Antibody: SHQ1 is the human homolog of yeast Shq1p, a protein that acts as an accessory factor in the assembly of H/ACA ribonucleoproteins. SHQ1 has been shown to bind the major H/ACA core protein and the pseudouridine synthase NAP57, but precedes the assembly role of NAF1 and of the other H/ACA core proteins. SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase.

NCBI Gene ID

55164

Swiss Prot

Q6PI26

Accession Number

NP_060600

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

SHQ1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1301 - Human Heart Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (94%)

Buffer

SHQ1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SHQ1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

IgG

Specificity

Multiple isoforms are known to exist.

Symbol

SHQ1

Positive Control 2

Cat. No. 10-501 - Human Heart Tissue Slide

NCBI Official Name

SHQ1 homolog (S. cerevisiae)

NCBI Organism

Homo sapiens

Background Reference 01

Ito T, Chiba T, Ozawa R, et al. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc. Natl. Acad. Sci. USA 2001; 98:4569-74.

Background Reference 02

Grozdanov PN, Roy S, Kittur N, et al. SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs. RNA 2009; 15:1188-97.

Other Product Names

SHQ1 Antibody: Shq1p, Protein SHQ1 homolog

Tested Applications

ELISA, WB, IF

Protein ID

56550033

Physical Properties

Liquid

Available Sizes

Curated Selection

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