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SEPT1 Antibody

Product Specifications

Background

SEPT1 Antibody: SEPT1 (also known as Septin 1), is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. SEPT1 was initially identified through yeast two-hybrid screening as an interaction partner for the serine/threonine kinase Aurora-B. During mitosis, SEPT1 localizes to the spindle pole, suggesting that it may play a role in cytokinesis and chromosome congression.

NCBI Gene ID

1731

Swiss Prot

Q8WYJ6

Accession Number

NP_443070

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

SEPT1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1207 - Raji Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Buffer

SEPT1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SEPT1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=6903

Fragment

IgG

Specificity

At least two isoforms of SEPT1 are known to exist. This antibody is predicted to not cross-react with other Septin protein family members.

Symbol

SEPT1

Positive Control 2

Cat. No. 17-007 - Raji Cell Slide

NCBI Official Name

Septin 1

NCBI Organism

Homo sapiens

Background Reference 01

Qi M, Yu W, Liu S, et al. Septin1, a new interaction partner for human serine/threonine kinase aurora-B. Biochem. Biophys. Res. Commun. 2005; 336:994-1000.

Background Reference 02

Russell SE and Hall PA. Septin genomics: a road less travelled. Biol. Chem. 2011; 392:763-7.

Background Reference 03

Zhu J, Qi ST, Wang YP, et al. Septin1 is required for spindle assembly and chromosome congression in mouse oocytes. Dev. Dyn. 2011; 240:2281-9.

Other Product Names

SEPT1 Antibody: LARP, SEP1, DIFF6, PNUTL3, Septin-1, LARP

Tested Applications

ELISA, WB, ICC, IF

Protein ID

431822382

Physical Properties

Liquid

Available Sizes

Curated Selection

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