What is the catalog number for WDR5 Antibody?

The catalog number for WDR5 Antibody is 6823.

What sizes are available for WDR5 Antibody?

WDR5 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does WDR5 Antibody come in?

WDR5 Antibody is available in 2 different pack sizes.

Is WDR5 Antibody in stock?

WDR5 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

WDR5 Antibody

Product Specifications

Background

WDR5 Antibody: WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.

NCBI Gene ID

11091

Swiss Prot

P61964

Accession Number

NP_060058

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

WDR5 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1210 - HEK293 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Rat: (100%), Mouse: (100%), Bovine: (100%)

Buffer

WDR5 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

WDR5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

WDR5 antibody is human specific. WDR5 antibody is predicted to not cross-react with other WDR family members.

Symbol

WDR5

Positive Control 2

Cat. No. 17-010 - HEK293 Cell Slide

NCBI Official Name

WD repeat domain 5

NCBI Organism

Homo sapiens

Background Reference 01

Smith TF, Gaitatzes C, Saxena K, et al. The WD repeat: a common architecture for diverse functions. Trends Biochem. Sci. 1999; 24:181-5.

Background Reference 02

Gori F and Demay MB. BIG-3, a novel WD-40 repeat protein, is expressed in the developing growth plate and accelerates chondrocyte differentiation in vitro. Endocrinology 2004; 145:1050-4.

Background Reference 03

Gori F, Friedman LG, and Demay MB. Wdr5, a WD-40 protein, regulates osteoblast differentiation during embryonic bone development. Dev. Biol. 2006; 295:498-506.

Background Reference 04

Ang YS, Tsai SY, Lee DF, et al. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 2011; 145:183-97.