YPEL1 Antibody

Product Specifications

Background

YPEL1 Antibody: YPEL1 (yippee-like 1) is thought to play a role in the epitheloid conversion of fibroblasts and the regulation of the cellular morphology. It is a 119 amino acid protein that localizes to the nucleus and belongs to a family of yippee-like proteins that include YPEL2 - 5, all of which localize to the centrosome and nucleus and are widely expressed in both adult and fetal tissue. The family of human YPEL proteins share a high degree of sequence homology with their rodent homologs, suggesting a conserved function between species. YPEL1 might be an important factor during the development and malignant transformation of tissues.

NCBI Gene ID

29799

Swiss Prot

O60688

Accession Number

NP_037445

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

YPEL1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1201 - HeLa Cell Lysate

Concentration

1 mg/mL

Buffer

YPEL1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

YPEL1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

YPEL1

Positive Control 2

Cat. No. 17-001 - HeLa Cell Slide

NCBI Official Name

Yippee-like 1

NCBI Organism

Homo sapiens

Background Reference 01

Farlie P, Reid C, Wilcox S, et al. YPEL1: a novel nuclear protein that induces an epithelial-like morphology in fibroblasts. Genes Cells 2001; 6:619-29.

Background Reference 02

Hosono K, Sasaki T, Minoshima S, et al. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. Gene 2004; 340: 31-43