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TSHZ1 Antibody

Product Specifications

Background

TSHZ1 Antibody: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.

NCBI Gene ID

10194

Swiss Prot

Q6ZSZ6

Accession Number

NP_005777

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

TSHZ1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1288 - A20 Cell Lysate

Concentration

1 mg/mL

Buffer

TSHZ1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TSHZ1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=6755

Fragment

IgG

Symbol

TSHZ1

Positive Control 2

Cat. No. 17-208 - A-20 Cell Slide

NCBI Official Name

Teashirt zinc finger homeobox 1

NCBI Organism

Homo sapiens

Background Reference 01

Caubit X, Core N, Boned A, et al. Vertebrate orthologues of the Drosophila region-specific patterning gene teashirt. Mech. Dev. 2000; 91:445-8.

Background Reference 02

Santos JS, Fonseca NA, Vieira CP, et al. Phylogeny of the Teashirt-related zinc finger (tshz) gene family and analysis of the developmental expression of tshz2 and tshz3 in the zebrafish. Dev. Dyn. 2010; 239:1010-8.

Background Reference 03

Core N, Caubit X, Metchat A, et al. Tshz1 is required for axial skeleton, soft palate and middle ear development in mice. Dev. Biol. 2007; 308:407-20

Background Reference 04

Kajiwara Y, Akram A, Katsel P, et al. FE65 binds teashirt, inhibiting expression of the primate-specific caspase-4. PLoS One 2009; 4:e5071.

Other Product Names

TSHZ1 Antibody: CAA, TSH1, NY-CO-33, SDCCAG33, Teashirt homolog 1, Antigen NY-CO-33

Tested Applications

ELISA, WB, ICC, IF

Protein ID

38201677

Physical Properties

Liquid

Available Sizes

Curated Selection

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