What is the catalog number for NKX2-6 Antibody?

The catalog number for NKX2-6 Antibody is 6751.

What sizes are available for NKX2-6 Antibody?

NKX2-6 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does NKX2-6 Antibody come in?

NKX2-6 Antibody is available in 2 different pack sizes.

Is NKX2-6 Antibody in stock?

NKX2-6 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

NKX2-6 Antibody

Product Specifications

Background

NKX2-6 Antibody: NKX2-6 (NK2 homeobox 6) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-6 is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are thought to be a cause for some congenital heart abnormalities.

NCBI Gene ID

137814

Swiss Prot

A6NCS4

Accession Number

NP_001129743

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

NKX2-6 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1401 - Mouse Heart Tissue Lysate

Concentration

1 mg/mL

Buffer

NKX2-6 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

NKX2-6 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

NKX2-6 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-6 are known to exist; this antibody will detect both isoforms

Symbol

NKX2-6

Positive Control 2

Cat. No. 10-901 - Human Spleen Tissue Slide

NCBI Official Name

NK2 homeobox 6

NCBI Organism

Homo sapiens

Background Reference 01

Copeland NG, Jenkins NA, and Harvey RP. The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively. Genomics 1994; 22:655-6.

Background Reference 02

Tanaka M, Kasahara H, Bartunkova S, et al. Vertebrate homologs of tinman and bagpipe: roles of the homeobox genes in cardiovascular development. Dev. Genet. 1998; 22:239-49.

Background Reference 03

Biben C, Hatzistavrou T, and Harvey RP. Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart. Mech. Dev. 1998; 73:125-7

Background Reference 04

Tanaka M, Schinke M, Liao HS, et al. Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx. Mol. Cell. Biol. 2001; 21:4391-8.