SPATA6 Antibody

Product Specifications

Background

SPATA6 Antibody: The development of spermatogonial stem cells into spermatozoa, i.e., spermatogenesis, is a highly ordered process that requires multiple proteins, including some that are testis-specific or testis-specific isoforms of genes that are expressed in other tissues. One such protein is SPATA6: while its full-length isoform is expressed in multiple tissues including thymus, brain and testis, the shorter isoform is expressed only in testis. It has some homology to the motor domain of kinesin related proteins and with the C. elegans neural calcium sensor protein NCS-2.

NCBI Gene ID

54558

Swiss Prot

Q9NWH7

Accession Number

NP_061946

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis

Purification

SPATA6 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1288 - A20 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Buffer

SPATA6 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SPATA6 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

At least three isoforms of SPATA6 are known to exist; this antibody will detect only the longest two isoforms. SPATA6 antibody is predicted to not cross-react with other SPATA protein family members.

Symbol

SPATA6

NCBI Official Name

Spermatogenesis associated 6

NCBI Organism

Homo sapiens

Background Reference 01

Venables JP. Alternative splicing in the testes. Curr. Opin. Genet. Dev. 2002; 12:615-9.

Background Reference 02

Oh C, Aho H, Shamsadin R, et al. Characterization, expression pattern and chromosomal localization of the spermatogenesis associated 6 gene (Spata6) . Mol. Human Reprod. 2003; 9:321-30.