RILPL1 Antibody

Product Specifications

Background

RILPL1 Antibody: While the function of the Rab interacting lysosomal protein-like 1 (RILPL1) remains unknown, the homologous protein RILP is a small GTPase that controls transport to endocytic compartments, suggesting RILPL1 may have similar functions. However, overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell, while overexpression of RILPL1 had no visible effect on the location or morphology of lysosomes.

NCBI Gene ID

353116

Swiss Prot

Q5EBL4

Accession Number

AAH89444

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

RILPL1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1473 - Rat Cerebellum Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (94%)

Buffer

RILPL1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

RILPL1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

At least three isoforms of RILPL1 are known to exist; this antibody will detect the two shorter isoforms. RILPL1 antibody is predicted to not cross-react with RILP.

Symbol

RILPL1

NCBI Official Name

Rab interacting lysosomal protein-like 1

NCBI Organism

Homo sapiens

Background Reference 01

Cantalupo G, Alifano P, Roberti V, et al. Rab-interacting lysosomal protein (RILP) : the Rab7 effector required for transport to lysosomes. EMBO J. 2001; 20:683-93

Background Reference 02

Wang T, Wong KK, and Hong W. A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. Mol. Biol. Cell 2004; 15:815-26