TMEM147 Antibody
Product Specifications
Background
TMEM147 Antibody: TMEM147 is a recently identified protein that associates with Nicalin and NOMO, forming a complex that is thought to be similar to the gamma-secretase complex. TMEM147 localizes to the endoplasmic reticulum (ER), and in zebrafish, is expressed during early development. TMEM147 also interacts with the M3 muscarinic receptor (M3R) in the ER and is thought to negatively its expression and function.
NCBI Gene ID
10430
Swiss Prot
Q9BVK8
Accession Number
NP_116024
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
TMEM147 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1224 - Daudi Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Buffer
TMEM147 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TMEM147 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=6453
Fragment
IgG
Symbol
TMEM147
NCBI Official Name
Transmembrane protein 147
NCBI Organism
Homo sapiens
Background Reference 01
Dettmer U, Kuhn PH, Abou-Ajram C, et al. Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex. J. Biol. Chem. 2010; 285:26174-81
Background Reference 02
Rosemond E, Rossi M, McMillin SM, et al. Regulation of M3 muscarinic receptor expression and function by transmembrane protein 147. Mol. Pharmacol. 2011; 79:251-61.
Other Product Names
TMEM147 Antibody: NIFIE14, Transmembrane protein 147, Protein NIFIE 14
Tested Applications
ELISA, WB
Protein ID
14249166
Physical Properties
Liquid
Available Sizes
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