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ARHGAP39 Antibody

Product Specifications

Background

ARHGAP39 Antibody: Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP39 (Rho GTPase activating protein 39) is a 1, 083 amino acid nuclear protein that contains one MyTH4 domain, one Rho GAP domain and two WW domains. It is encoded by a gene located on human chromosome 8, which is associated with a variety of diseases and malignancies. ARHGAP39 regulates robo signaling and plays important roles in axon guidance.

NCBI Gene ID

80728

Swiss Prot

Q9C0H5

Accession Number

NP_079527

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

ARHGAP39 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1288 - A20 Cell Lysate

Concentration

1 mg/mL

Buffer

ARHGAP39 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

ARHGAP39 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=6445

Fragment

IgG

Specificity

ARHGAP39 antibody is predicted to not cross-react with other RhoGAP protein family members.

Symbol

ARHGAP39

NCBI Official Name

Rho GTPase activating protein 39

NCBI Organism

Homo sapiens

Background Reference 01

Takai Y, Sasaki T, and Matozaki T. Small GTP-binding proteins. Physiol. Rev. 2001; 81:153-208.

Background Reference 02

Hu H, Li M, Labrador JP, et al. Cross GTPase-activating protein (CrossGAP) /Vilse links the Roundabout receptor to Rac to regulate midline repulsion. Proc. Natl. Acad. Sci. USA 2005; 102:4613-8

Background Reference 03

Nusbaum C, Mikkelsen TS, Zody MC, et al. DNA sequence and analysis of human chromosome 8. Nature 2006; 439:331-5

Background Reference 04

Lundströ m A, Gallio M, Englund C, et al. Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons. Genes Dev. 2004; 18:2161-71.

Other Product Names

ARHGAP39 Antibody: CrGAP, Vilse, KIAA1688, Rho GTPase-activating protein 39

Tested Applications

ELISA, WB

Protein ID

58331179

Physical Properties

Liquid

Available Sizes

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