HDGFRP2 Antibody
Product Specifications
Background
HDGFRP2 Antibody: Hepatoma-derived growth factor-related protein 2 (HDGFRP2) is a widely expressed member of protein family that contains the HDGF related proteins 1-4 and lens epithelial derived growth factor (LEDGF) . These family members show extensive homology at the amino terminus (termed the hath region) . Little is known of the role of HDGFRP2, but like the related LEDGF, HDGFRP2 can bind HIV-1 integrase and stimulate HIV-1 integrase activity in vitro.
NCBI Gene ID
84717
Swiss Prot
Q7Z4V5
Accession Number
EAW69215
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
HDGFRP2 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1462 - Rat Lung Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Chicken: (94%)
Buffer
HDGFRP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
HDGFRP2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
At least two isoforms of HDGFRP2 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other HDGFRP family members
Symbol
HDGFRP2
NCBI Official Name
Hepatoma-derived growth factor-related protein 2
NCBI Organism
Homo sapiens
Background Reference 01
El-Tahir HM, Dietz F, Dringen R, et al. Expression of Hepatoma-derived growth factor family members in the adult central nervous system. BMC Neurosci. 2006; 7:6.
Background Reference 02
Izumoto Y, Kuroda T, Harada H, et al. Hepatoma-derived growth factor belongs to a gene family in mice showing significant homology in the amino terminus. Biochem. Biophys. Res. Commun. 1997; 238:26-32
Background Reference 03
Cherepanov P, Devroe E, Silver PA, et al. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. J. Biol. Chem. 2004; 279:48883-92.
Other Product Names
HDGFRP2 Antibody: HDGF2, HDGF2, UNQ785/PRO1604, Hepatoma-derived growth factor-related protein 2, Hepatoma-derived growth factor 2, HRP-2
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
48255931
Physical Properties
Liquid
Available Sizes
Frequently Asked Questions
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