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HDGFRP2 Antibody

Product Specifications

Background

HDGFRP2 Antibody: Hepatoma-derived growth factor-related protein 2 (HDGFRP2) is a widely expressed member of protein family that contains the HDGF related proteins 1-4 and lens epithelial derived growth factor (LEDGF) . These family members show extensive homology at the amino terminus (termed the hath region) . Little is known of the role of HDGFRP2, but like the related LEDGF, HDGFRP2 can bind HIV-1 integrase and stimulate HIV-1 integrase activity in vitro.

NCBI Gene ID

84717

Swiss Prot

Q7Z4V5

Accession Number

EAW69215

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

HDGFRP2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1462 - Rat Lung Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Chicken: (94%)

Buffer

HDGFRP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

HDGFRP2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

At least two isoforms of HDGFRP2 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other HDGFRP family members

Symbol

HDGFRP2

NCBI Official Name

Hepatoma-derived growth factor-related protein 2

NCBI Organism

Homo sapiens

Background Reference 01

El-Tahir HM, Dietz F, Dringen R, et al. Expression of Hepatoma-derived growth factor family members in the adult central nervous system. BMC Neurosci. 2006; 7:6.

Background Reference 02

Izumoto Y, Kuroda T, Harada H, et al. Hepatoma-derived growth factor belongs to a gene family in mice showing significant homology in the amino terminus. Biochem. Biophys. Res. Commun. 1997; 238:26-32

Background Reference 03

Cherepanov P, Devroe E, Silver PA, et al. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. J. Biol. Chem. 2004; 279:48883-92.

Other Product Names

HDGFRP2 Antibody: HDGF2, HDGF2, UNQ785/PRO1604, Hepatoma-derived growth factor-related protein 2, Hepatoma-derived growth factor 2, HRP-2

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

48255931

Physical Properties

Liquid

Available Sizes

Frequently Asked Questions

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