TMEM88 Antibody
Product Specifications
Background
TMEM88 Antibody: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.
NCBI Gene ID
92162
Swiss Prot
Q6PEY1
Accession Number
EAW90125
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
TMEM88 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1303 - Human Brain Tissue Lysate
Concentration
1 mg/mL
Buffer
TMEM88 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TMEM88 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=6397
Fragment
IgG
Specificity
At least two isoforms of TMEM88 are known to exist; this antibody will recognize both isoforms.
Symbol
TMEM88
NCBI Official Name
Transmembrane protein 88
NCBI Organism
Homo sapiens
Background Reference 01
Lee HJ, Finklestein D, Li X, et al. Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein. J. Biol. Chem. 2010; 285:41549-56.
Other Product Names
TMEM88 Antibody: TMEM88A, Transmembrane protein 88
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
44662813
Physical Properties
Liquid
Available Sizes
Curated Selection
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