ApoA1 Antibody
Product Specifications
Background
ApoA1 Antibody: Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma, which is correlated with cardiovascular disease. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.
NCBI Gene ID
335
Swiss Prot
P02647
Accession Number
P02647
Host
Rabbit
Reactivity
Human, Chicken
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
ApoA1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Chicken Liver Lysate
Concentration
1 mg/mL
Buffer
ApoA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ApoA1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=6265
Fragment
IgG
Symbol
APOA1
NCBI Official Name
Apolipoprotein A-I
NCBI Organism
Homo sapiens
Background Reference 01
Zhu X, Wu G, Zeng W, et al. Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties. J. Lipid Res. 2005; 46:1303-11
Background Reference 02
Sorci-Thomas MG, Prack MM, Dashti N, et al. Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins. J. Lipid Res. 1989; 30:1397-403
Background Reference 03
Lai C-Q, Parnell LD, and Ordovas JM. The APOA1 /C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk. Curr. Opin. Lipid. 2005; 16:153-66
Other Product Names
ApoA1 Antibody: Apolipoprotein A-I, Apolipoprotein A1, Apo-AI
Tested Applications
ELISA, WB
Protein ID
113992
Physical Properties
Liquid
Available Sizes
Curated Selection
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