TMEM192 Antibody

Product Specifications

Background

TMEM192 Antibody: TMEM192 is a widely expressed, four transmembrane protein that localizes to late endosomal/lysosomal membranes. This localization is mediated by two dileucine motifs present at the amino-terminus of TMEM192. A cysteine residue near the carboxy residue is responsible for disulfide bond formation in TMEM192 homodimers. Little is known about the function of this protein.

NCBI Gene ID

201931

Swiss Prot

Q8IY95

Accession Number

NP_001093859

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

TMEM192 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1220 - SK-N-SH Cell Lysate

Concentration

1 mg/mL

Buffer

TMEM192 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TMEM192 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

At least two isoforms of TMEM192 are known to exist; this antibody will recognize both. TMEM192 antibody is predicted to not cross-react with other TMEM proteins.

Symbol

TMEM192

NCBI Official Name

Transmembrane protein 192

NCBI Organism

Homo sapiens

Background Reference 01

Schroder B, Wrocklage C, Hasilik A, et al. Molecular characterisation of ‘transmembrane protein 192' (TMEM192, a novel protein of the lysosomal membrane. Biol. Chem. 2010; 391:695-704.