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SLAMF9 Antibody

Product Specifications

Background

SLAMF9 Antibody: The SLAM (signalling lymphocyte activation molecule) family is a novel group of receptors on T cells in modulating the immune response. SLAMF9, also known as CD2F-10 or CD84 homolog, is a 289 amino acid type I transmembrane protein that shares 58% identity with the mouse protein. The SLAMF9 protein is predominantly expressed in hematopoietic tissues and contains an extracellular region with only two N-linked glycosylation sites, a 20-residue transmembrane region and a highly positively charged 30-residue cytoplasmic tail, suggesting a role for SLAMF9 as an adhesion molecule. SLAMF9 is thought to function in the immune response as a coreceptor for lymphocyte activation.

NCBI Gene ID

89886

Swiss Prot

Q96A28

Accession Number

NP_001139645

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

SLAMF9 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1405 - Mouse Kidney Tissue Lysate

Concentration

1 mg/mL

Buffer

SLAMF9 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SLAMF9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

SLAMF9 antibody is predicted to not cross-react with other SLAM protein family members.

Symbol

SLAMF9

Positive Control 2

Cat. No. 10-401 - Human Kidney Tissue Slide

NCBI Official Name

SLAM family member 9

NCBI Organism

Homo sapiens

Background Reference 01

Veillette A and Latour S. The SLAM family of immune-cell receptors. Curr. Opin. Immunol. 2003; 15:277-85.

Background Reference 02

Veillette A. SLAM family receptors regulate immunity with and without SAP-related adaptors. J. Exp. Med. 2004; 199:1175-8.

Background Reference 03

Fennelly JA, Tiwari B, Davis SJ, et al. CD2F-10: a new member of the CD2 subset of the immunoglobulin superfamily. Immunogenetics 2001; 53:599-602.

Background Reference 04

Detre C, Keszei M, Romero X, et al. SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Semin. Immunopathol. 2010; 32:157-71.

Other Product Names

SLAMF9 Antibody: CD2F10, CD84H1, SF2001, CD2F-10, CD84-H1, CD2F10, UNQ1938/PRO4421, SLAM family member 9, CD2 family member 10

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

226342990

Physical Properties

Liquid

Available Sizes

Frequently Asked Questions

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