NALP13 Antibody

Product Specifications

Background

NALP13 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.

NCBI Gene ID

126204

Swiss Prot

Q86W25

Accession Number

EAW72420

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

NALP13 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1204 - K562 Cell Lysate

Concentration

1 mg/mL

Buffer

NALP13 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

NALP13 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

NLRP13

Positive Control 2

Cat. No. 17-004 - K-562 Cell Slide

NCBI Official Name

NLR family, pyrin domain containing 13

NCBI Organism

Homo sapiens

Background Reference 01

Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.

Background Reference 02

Tian X, Pascal G, and Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive system. BMC Evol. Biol.2009; 9:202.

Other Product Names

NALP13 Antibody: NOD14, PAN13, NALP13, CLR19.7, NOD14, NACHT, LRR and PYD domains-containing protein 13, Nucleotide-binding oligomerization domain protein 14