What is the catalog number for IDH2 Antibody?

The catalog number for IDH2 Antibody is 5821.

What sizes are available for IDH2 Antibody?

IDH2 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does IDH2 Antibody come in?

IDH2 Antibody is available in 2 different pack sizes.

Is IDH2 Antibody in stock?

IDH2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

IDH2 Antibody

Product Specifications

Background

IDH2 Antibody: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+) . Two NADP (+) -dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. Both IDH1 and IDH2 play significant roles in the tricarboxylic acid cycle (TCA), and defects in IDH1 as well as IDH2 have been implicated in the development of glioma as well as other malignancies.

NCBI Gene ID

3418

Swiss Prot

P48735

Accession Number

NP_002159

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

IDH2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1301 - Human Heart Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (88%)

Buffer

IDH2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

IDH2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

IDH2

NCBI Official Name

Isocitrate dehydrogenase 2 (NADP+), mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Geisbrecht BV and Gould SJ. The human PICD gene encodes a cytoplasmic and peroxisomal NADP (+) -dependent isocitrate dehydrogenase. J. Biol. Chem.1999; 274:30527-33.

Background Reference 02

Przybyla-Zawislak B, Gadde DM, Ducharme K, et al. Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics1999; 152:153-66.