TINP1 Antibody

Product Specifications

Background

TINP1 Antibody: TINP1 (TGF-beta inducible nuclear protein 1), also known as NSA2 (Nop seven-associated 2), is a highly conserved nucleolar protein essential for large ribosomal subunit biogenesis. NSA2 is broadly expressed in human tissues and cultured cell lines, and located in the nucleolus of the cell. It is thought to be involved in cell proliferation and cell cycle regulation.

NCBI Gene ID

10412

Swiss Prot

O95478

Accession Number

NP_055701

Host

Chicken

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

TINP1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1463 - Rat Brain Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Buffer

TINP1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TINP1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgY

Symbol

NSA2

Positive Control 2

Cat. No. 10-301 - Human Brain Tissue Slide

NCBI Official Name

NSA2 ribosome biogenesis homolog (S. cerevisiae)

NCBI Organism

Homo sapiens

Background Reference 01

Lebreton A, Saveanu C, Decourty L, et al. Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J. Biol. Chem.2006; 281:27099-108.

Background Reference 02

Zhang H, Ma X, Shi T, et al. NSA2, a novel nucleolus protein regulates cell proliferation and cell cycle. Biochem. Biophys. Res. Commun.2010; 391:651-8.