TMEM184A Antibody

Product Specifications

Background

TMEM184A Antibody: TMEM184A, a multi-pass transmembrane protein, belongs to the UPF0206 family. While the exact function of TMEM184A remains unclear, it is known to be expressed at high levels in the developing testis. TMEM184A may mediate sex-specific signaling events during Sertoli cell differentiation. The restricted expression of this gene in Sertoli cells suggests a role for the encoded protein in the development and/or continued function of that cell type. Ectopic expression of TMEM184A in female genital ridges resulted in failure of gonocytes to enter meiosis.

NCBI Gene ID

202915

Swiss Prot

Q6ZMB5

Accession Number

NP_001091089

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

TMEM184A Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 10-301 - Human Brain Tissue Slide

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (80%)

Buffer

TMEM184A Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TMEM184A antibody can be stored at 4˚ C for up to one year. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

TMEM184A

NCBI Official Name

Transmembrane protein 184A

NCBI Organism

Homo sapiens

Background Reference 01

Svingen T, Beverdam A, Bernard P, et al. Sex-specific expression of a novel gene Tmem184a during mouse testis differentiation. Reproduction2007; 133:983-9.

Background Reference 02

Svingen T, Wilhelm D, Combes AN, et al. Ex vivo magnetofection: a novel strategy for the study of gene function in mouse organogenesis. Dev Dyn.2009; 238:956-64.