CAZIP Antibody
Product Specifications
Background
CAZIP Antibody: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1) -dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
NCBI Gene ID
23281
Swiss Prot
Q5JR59
Accession Number
NP_001028774
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
CAZIP Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1288 - A20 Cell Lysate
Concentration
1 mg/mL
Buffer
CAZIP Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CAZIP antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=5639
Fragment
IgG
Symbol
MTUS2
NCBI Official Name
Microtubule associated tumor suppressor candidate 2
NCBI Organism
Homo sapiens
Background Reference 01
Du Puy L, Beqqali A, Monshouwer-Kloots J, et al. CAZIP, a novel protein expressed in the developing heart and nervous system. Dev. Dyn.2009; 238:2903-11.
Background Reference 02
Jiang K, Wang J, Liu J, et al. TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep.2009; 10:857-65.
Other Product Names
CAZIP Antibody: ICIS, CAZIP, TIP150, KIAA0774, Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Tracking protein of 150 kDa
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
140161498
Physical Properties
Liquid
Available Sizes
Curated Selection
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